Paired-Duplication Signatures Mark Cryptic Inversions and Other Complex Structural Variation

نویسندگان
چکیده

برای دانلود رایگان متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Simultaneous Structural Variation Discovery in Multiple Paired-End Sequenced Genomes

As whole genome shotgun sequencing (WGSS) becomes more accessible using high-throughput sequencing technologies, undertaking comparative studies among different individuals (based on population, race, or genetic disease) is the next logical step. In this paper, we propose a paradigm shift in variation comparative studies (specifically structural variation) away from the conventional two step ap...

متن کامل

Simultaneous structural variation discovery among multiple paired-end sequenced genomes.

With the increasing popularity of whole-genome shotgun sequencing (WGSS) via high-throughput sequencing technologies, it is becoming highly desirable to perform comparative studies involving multiple individuals (from a specific population, race, or a group sharing a particular phenotype). The conventional approach for a comparative genome variation study involves two key steps: (1) each paired...

متن کامل

Cryptic genetic variation

What is cryptic genetic variation? Cryptic genetic variation refers to unexpressed, bottled-up genetic potential. It is not normally seen, but is expressed under abnormal conditions such as in a new environment or a different genetic background. In a sense, the measurable component of normal variation is just the tip of an iceberg of genetic possibilities that are hidden below the visible surface.

متن کامل

Using Program MARK for assessing survival in cryptic threatened species

Program MARK is a sophisticated computer program that can analyse markrecapture data and produce survival and population estimates which can then be used in a population viability analysis. The ability to detect trends in survival and population size over time enables conservation managers to make good decisions in species management. This report is a step-by-step guide to the basics of the MAR...

متن کامل

Cryptic genetic variation and paraphyly in ravens.

Widespread species that are morphologically uniform may be likely to harbour cryptic genetic variation. Common ravens (Corvus corax) have an extensive range covering nearly the entire Northern Hemisphere, but show little discrete phenotypic variation. We obtained tissue samples from throughout much of this range and collected mitochondrial sequence and nuclear microsatellite data. Our study rev...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

ژورنال

عنوان ژورنال: The American Journal of Human Genetics

سال: 2015

ISSN: 0002-9297

DOI: 10.1016/j.ajhg.2015.05.012